Regenerate

What we have thought about

For regeneration it is especially important to supply your body with all necessary nutrients.

First of all, this includes an adequate calorie intake with balanced amounts of fats (especially the polyunsaturated omega 3 and 6 fatty acids), carbohydrates and proteins (protein). Proteins in particular play a very important role. According to studies, the most important amino acids for wound healing are arginine and glutamine - preferably in combination with the anti-inflammatory omega 3 fatty acids. The requirement varies greatly and can increase many times over.

Micronutrients are very important because they regulate the immune system, play a central role in the function of enzymes and in the formation of new cells and collagen. They can also contribute to the reduction of free radicals.

The fat-soluble vitamin E is a radical scavenger and protects your cells from oxidative stress.

Vitamin A is also a fat-soluble vitamin with special properties when it comes to collagen synthesis, cell division and differentiation (=specialization). It is important for a stable collagen network to develop and also contributes to the normal function of the immune system to keep the wound clean.

Everyone knows that vitamin C is an excellent antioxidant and is important for a normal immune system and energy metabolism - it is credited with reducing mast cell activity and thus heparin release so that the wound does not bleed as much. In addition, it is also needed for collagen synthesis as well as many enzymatic processes. That is why the demand is so high.

Vitamin B5 is also called panthothenic acid or "anti-stress vitamin" because it helps us maintain a normal energy metabolism and is important in the synthesis of certain neurotransmitters (messengers between nerves). Chemical compounds - so called amides - that are formed from pathothenic acid have antimicrobial properties and keep our wounds clean. But panthothenic acid can do much more: it improves skin barrier function and moisturizes our skin. Coenzyme A is also formed from pathothenic acid.

Copper and selenium belong to the essential trace elements and are cofactors of numerous enzymes that reduce cell damage.

Calcium not only plays an important role in building new muscle cells and bone structures, but is also a prerequisite for our blood clotting to function normally.

Zinc is a component of numerous enzymes and essential for the synthesis of nucleic acids (i.e. our DNA) and proteins of regenerating cells. In wound healing, zinc serves, among other things, as a cofactor for the synthesis of collagen and helps to protect the cells from oxidative stress.

Through its influence on cell division, zinc can promote the formation of new cells.

There are large differences in the bioavailability of different zinc preparations. Zinc sulphate has been well studied and is considered the standard of bioavailability. It is best absorbed when taken on an empty stomach.

Food supplements

Do not exceed the recommended daily intake. Food supplements are not a substitute for a balanced and varied diet.

Keep out of reach of children.

Storage

Store in a dry, cool place away from light. Keep away from heat and direct sunlight.

Packing

Packed in a light-protected PETPacker can - free of BPA.

What else can I do for good wound healing?

It is important that the wound remains clean (i.e. free of infection) and well supplied with blood. In the first 24 h it may be useful to additionally cool the wound to reduce bruising and swelling - but you should discuss this in detail with your surgeon.

As nicotine contributes to the constriction of small blood vessels and the activation of blood platelets, it is important not to smoke.

In addition, the wound should not be under tension - this means rest and possibly elevation are very useful.

If you have diabetes, optimal blood sugar control is particularly important in this phase.

Dehydration can impair wound healing, so please drink enough (unsweetened) fluids, i.e. approx. 1.5-2 l per day.

Ingredients

*Percentage of the nutrient reference quantity according to Regulation (EU) No. 1169/2011

**no reference available

Capsule shell: hydroxpropylmethylcellulose, guaranteed free of PEG and carrageenan

No fillers.

Allergens: none contained

Capsule weight: 921.8 mg

Net weight per can (120 capsules): 110,6 g

Recommended intake / dosage

Take 2 capsules with 200 ml water twice daily before meals.

We recommend taking it for a period of at least 6 weeks.

Our quality promise

Our capsules are made of HPMC (hydroxypropylmethylcellulose) - i.e. vegetable cellulose and do not contain any potentially harmful substances such as PEG (polyethylene glycol) or carrageenan.

All ingredients are tested in an HACCP- and GMP-certified plant in Austria according to the quality standards valid in the EU and are also encapsulated here.

We do not use any potentially harmful release agents or superplasticisers such as titanium dioxide or silicon dioxide; if necessary, we use microcrystalline cellulose as a filler.

All our products are GMO-free, gluten-free and lactose-free. All products are also suitable for a vegan diet.

For all those who would like to know more:

Here you will find selected studies that have investigated potential benefits of the substances used or simply explain the topic of wound healing and its support through nutrition in more detail:

Zinc:

Kogan S, Sood A, Garnick MS. Zinc and Wound Healing: A Review of Zinc Physiology and Clinical Applications. Wounds. 2017 Apr;29(4):102-106. PMID: 28448263.

Desneves KJ, Todorovic BE, Cassar A, Crowe TC. Treatment with supplementary arginine, vitamin C and zinc in patients with pressure ulcers: a randomised controlled trial. Clin Nutr. 2005 Dec;24(6):979-87. doi: 10.1016/j.clnu.2005.06.011. epub 2005 Nov 15. PMID: 16297506.

Vitamin A:

Zinder R, Cooley R, Vlad LG, Molnar JA. Vitamin A and wound healing. Nutr Clin Pract. 2019 Dec;34(6):839-849. doi: 10.1002/ncp.10420. PMID: 31697447.

Wound healing:

Rawson ES, Miles MP, Larson-Meyer DE. Dietary Supplements for Health, Adaptation, and Recovery in Athletes. Int J Sport Nutr Exerc Metab. 2018 Mar 1;28(2):188-199. doi: 10.1123/ijsnem.2017-0340. epub 2018 Feb 19. PMID: 29345167.

Quain AM, Khardori NM. Nutrition in Wound Care Management: A Comprehensive Overview. Wounds. 2015 Dec;27(12):327-35. PMID: 27447105.

Palmieri B, Vadalà M, Laurino C. Nutrition in wound healing: investigation of the molecular mechanisms, a narrative review. J Wound Care. 2019 Oct 2;28(10):683-693. doi: 10.12968/jowc.2019.28.10.683. PMID: 31600106.

Tipton KD. Nutritional Support for Exercise-Induced Injuries. Sports Med. 2015 Nov;45 Suppl 1:S93-104. doi: 10.1007/s40279-015-0398-4. PMID: 26553492; PMCID: PMC4672013.

Smith-Ryan AE, Hirsch KR, Saylor HE, Gould LM, Blue MNM. Nutritional Considerations and Strategies to Facilitate Injury Recovery and Rehabilitation. J Athl Train. 2020 Sep 1;55(9):918-930. doi: 10.4085/1062-6050-550-19. PMID: 32991705; PMCID: PMC7534941.

Scholl D, Langkamp-Henken B. Nutrient recommendations for wound healing. J Intraven Nurs. 2001;24(2):124 -32.

Baron JM, Glatz M, Proksch E. Optimal Support of Wound Healing: New Insights. Dermatology. 2020;236(6):593-600. doi: 10.1159/000505291. epub 2020 Jan 17. PMID: 31955162.

Vitamin C:

Fukushima R, Yamazaki E. Vitamin C requirement in surgical patients. Curr Opin Clin Nutr Metab Care. 2010;13(6):669 -76.

Blass SC, Goost H, Tolba RH, et al. Time to wound closure in trauma patients with disorders in wound healing is shortened by supplements containing antioxidant micronutrients and glutamine: A PRCT. Clinical Nutrition 2012;31:469 -75.

Moores J. Vitamin C: a wound healing perspective. Br J Community Nurs. 2013 Dec;Suppl:S6, S8-11. doi: 10.12968/bjcn.2013.18.sup12.s6. PMID: 24796079.

Vitamin B5 / pathothenic acid:

Gheita AA, Gheita TA, Kenawy SA. The potential role of B5: A stitch in time and switch in cytokine. Phytother Res. 2020 Feb;34(2):306-314. doi: 10.1002/ptr.6537. epub 2019 Nov 5. PMID: 31691401.